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Article

MicroRNA-378 regulates oocyte maturation via the suppression of aromatase in porcine cumulus cells

28 Jan 2015

Abstract excerpt

We sought to investigate whether miR-378 plays a role in cumulus cells and whether the manipulation of miRNA levels in cumulus cells influences oocyte maturation in vitro. Cumulus-oocyte complexes (COCs) from ovarian follicles had significantly lower levels of precursor and mature miR-378 in cumulus cells surrounding metaphase II (MII) oocytes than cumulus cells surrounding germinal vesicle (GV) oocytes,...

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PMID: 25628423
DOI: 10.1152/ajpendo.00480.2014

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