Article
The C-allele of tissue inhibitor of metalloproteinases 2 is associated with increased magnitude of QT dispersion prolongation in elderly Chinese - 4-year follow-up study.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2000
Lin Tsung-Hsien, Chiu Herng-Chia, Lee Ya-Ting, Su Ho-Ming, Juo Suh-Hang Hank, Voon Wen-Chol, Lai Wen-Ter, Sheu Sheng-Hsiung
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMP) and tissue inhibitor of metalloproteinases (TIMP) trigger the signal cascade instigating cardiac remodeling and fibrosis, which lead to changes of repolarization variables. We investigate the influence of MMP9-1562 C/T and TIMP2-418 G/C gene polymorphis...
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