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Article

Norwalk Virus RNA Is Infectious in Mammalian Cells

14 Sept 2007

Abstract excerpt

Human noroviruses are positive-sense RNA viruses and are the leading cause of epidemic acute viral gastroenteritis in developed countries. The absence of an in vitro cell culture model for human norovirus infection has limited the development of effective antivirals and vaccines. Human histo-blood group antigens have been regarded as receptors for norovirus infection, and expression of the alpha(1,2)...

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PMID: 17855551
DOI: 10.1128/jvi.01489-07

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