Article
Carboxy-terminal sequence variation of LMP1 gene in Epstein-Barr-virus-associated mononucleosis and tumors from Serbian patients.
Journal of medical virology - 1 Apr 2012
Banko Ana, Lazarevic Ivana, Cupic Maja, Stevanovic Goran, Boricic Ivan, Jovanovic Tanja
Abstract excerpt
Seven strains of Epstein-Barr virus (EBV) are defined based on C-terminal sequence variations of the latent membrane protein 1 (LMP1). Some strains, especially those with a 30-bp deletion, are thought to be related to tumorigenic activity and geographical localization. The aims of the study were to determine the prevalence of different LMP1 strains and to investigate sequence variation in the C-terminal region of...
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