Transketolase A, an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR.

Abstract excerpt

The Escherichia coli marRAB operon specifies two regulatory proteins, MarR (which represses) and MarA (which activates expression of the operon). The latter controls expression of multiple other chromosomal genes implicated in cell physiology, multiple drug resistance and virulence. Using randoml...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Dimerization
• Share to Drug Resistance, Multiple, Bacterial
• Share to Escherichia coli