Article
Characterization of an Escherichia coli O157:H7 marR mutant.
International journal of food microbiology - 25 Aug 2003
Yaron Sima, White David G, Matthews Karl R
Abstract excerpt
One mechanism for generation of multiple antibiotic resistance in enteric bacteria involves the global regulatory system marRAB. The operon, when induced, encodes for resistance to structurally and functionally unrelated antibiotics. Exposure of Escherichia coli O157:H7 to increasing levels of chloramphenicol (CHL) resulted in survival of mutants that were resistant to the inducing agent and to tetracycline...
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