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Development of a Specific Monoclonal Antibody to Detect Male Cells Expressing the RPS4Y1 Protein

18 Feb 2021

Abstract excerpt

Hemophilia is an X-linked recessive bleeding disorder. In pregnant women carrier of hemophilia, the fetal sex can be determined by non-invasive analysis of fetal DNA circulating in the maternal blood. However, in case of a male fetus, conventional invasive procedures are required for the diagnosis of hemophilia. Fetal cells, circulating in the maternal bloodstream, are an ideal target for a safe non-invasive...

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PMID: 33670450
DOI: 10.3390/ijms22042001

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