Article
Studies in 3,523 Norwegians and meta-analysis in 11,571 subjects indicate that variants in the hepatocyte nuclear factor 4 alpha (HNF4A) P2 region are associated with type 2 diabetes in Scandinavians.
Diabetes - 1 Dec 2007
Johansson Stefan, Raeder Helge, Eide Stig A, Midthjell Kristian, Hveem Kristian, Søvik Oddmund, Molven Anders, Njølstad Pål Rasmus
Abstract excerpt
OBJECTIVE: Recent publications have found an association between common variants near the hepatocyte nuclear factor 4 alpha (HNF4A) P2 promoter and type 2 diabetes in some populations but not in others, and the role for HNF4A in type 2 diabetes has remained unclear. In an attempt to address these inconsistencies, we investigated HNF4A single nucleotide polymorphisms (SNPs) in a large population-based sample and...
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