Article
Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 2. Drug resistance, molecular karyotypes and the mdr1 genotype of recent isolates.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000
Babiker H A, Creasey A M, Bayoumi R A, Walliker D, Arnot D E
Abstract excerpt
Isolates of Plasmodium falciparum from a Sudanese village have been collected as part of a study of parasite genetic diversity during seasonal malaria epidemics. The sensitivity in vitro to chloroquine, pyrimethamine and mefloquine of these isolates has been determined. To assess the utility of pulse field gel chromosome separations in isolate characterization, 18 samples from individual patients in a single...
Topics
- Animals
- Blotting, Southern
- Drug Resistance
- Electrophoresis, Gel, Pulsed-Field
- Genetic Variation
- Genotype
- Humans
- Karyotyping
- Malaria
- Plasmodium falciparum