Article
Local differentiation in Plasmodium falciparum drug resistance genes in Sudan.
Parasitology - 1 May 2003
Abdel-Muhsin A A, Mackinnon M J, Awadalla P, Ali E, Suleiman S, Ahmed S, Walliker D, Babiker H A
Abstract excerpt
Studies of population genetic structure of parasites can be used to infer which parasite genes are under selection. Here, the population structure of 4 genes associated with drug resistance of Plasmodium falciparum (the chloroquine resistance transporter, pfcrt, dihydrofolate reductase, dhfr, dihydropteroate synthase, dhps, and multi-drug resistance, pfmdr-1) were examined in parasite populations in 3 villages in...
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