Article
Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies.
The Journal of biological chemistry - 26 Oct 2007
Bishop Brooke, Dasgupta Jhimli, Klein Michael, Garcea Robert L, Christensen Neil D, Zhao Rui, Chen Xiaojiang S
Abstract excerpt
Human papillomaviruses (HPVs) are known etiologic agents of cervical cancer. Vaccines that contain virus-like particles (VLPs) made of L1 capsid protein from several high risk HPV types have proven to be effective against HPV infections. Raising high levels of neutralizing antibodies against each...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
