Article
HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain.
Virology - 20 Jan 2000
Ludmerer S W, McClements W L, Wang X M, Ling J C, Jansen K U, Christensen N D
Abstract excerpt
Characterization of the regions of human papillomaviruses (HPVs) that elicit neutralizing immune responses supports studies on viral infectivity and provides insight for the development and evaluation of prophylactic vaccines. HPV11 is a major etiologic agent of genital warts and a likely vaccine candidate. A conformationally dependent epitope for the binding of three neutralizing monoclonal antibodies (mAbs) has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
