Article
Connecting the dots between septins and the DNA damage checkpoint.
Cell - 7 Sept 2007
Kinoshita Makoto, Takeda Shunichi
Abstract excerpt
In budding yeast, septins are involved in the morphogenesis checkpoint and the DNA damage checkpoint, both of which regulate cell-cycle progression. In this issue of Cell, Kremer et al. (2007) link septins to DNA damage in mammalian cells by identifying a new signaling pathway that includes the adaptors SOCS7 and NCK. As NCK controls actin dynamics, this pathway may connect DNA damage responses and cellular...
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