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Article

Functional polymorphisms in the promoter region of macrophage migration inhibitory factor and chronic gastritis.

International journal of molecular medicine - 1 Oct 2007

Arisawa Tomiyasu, Tahara Tomomitsu, Shibata Tomoyuki, Nagasaka Mitsuo, Nakamura Masakatsu, Kamiya Yoshio, Fujita Hiroshi, Nakamura Masahiko, Yoshioka Daisuke, Arima Yuko, Okubo Masaaki, Hirata Ichiro, Nakano Hiroshi

Abstract excerpt

Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator, which plays a pivotal role in inflammatory and immune diseases. We attempted to clarify associations of the functional polymorphisms of the MIF gene promoter with the development of chronic gastritis. The study was performed with 290 stocked DNAs from subjects with no evidence of gastric malignancy. We employed the PCR-SSCP method to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17786285

Genes

MIF

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