Article
The osmolyte taurine protects against ultraviolet B radiation-induced immunosuppression.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2007
Rockel Nicole, Esser Charlotte, Grether-Beck Susanne, Warskulat Ulrich, Flögel Ulrich, Schwarz Agatha, Schwarz Thomas, Yarosh Daniel, Häussinger Dieter, Krutmann Jean
Abstract excerpt
Organic osmolytes, such as taurine, are involved in cell volume homeostasis and cell protection. Epidermal keratinocytes possess an osmolyte strategy, i.e., they take up taurine upon hyperosmotic stress and express the corresponding transporter TAUT. UVB irradiation also triggers taurine uptake and TAUT expression in this cell type. We therefore asked whether taurine plays a role in photoprotection. By using a...
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