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Article

Endoderm and Pancreatic Islet Lineage Differentiation from Human Embryonic Stem Cells

1 Jun 2006

Abstract excerpt

Human embryonic stem cells (HESCs) are a potential source of insulin-producing tissue for transplantation. Recent studies have begun to define factors that promote definitive endoderm formation from HESCs, but conditions permitting complete islet specification in vitro have not been described. Here, we study spontaneous differentiation of HESCs to definitive endoderm and pancreatic progenitor cells, and begin to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16776601
DOI: 10.1089/clo.2006.8.96

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