Article
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2007
Hall Andrew J, Quinnell Rupert J, Raiko Andrew, Lagog Moses, Siba Peter, Morroll Shaun, Falcone Franco H
Abstract excerpt
Human chitotriosidase (CHIT1) is a chitinolytic enzyme with suggested anti-fungal properties. Previous studies have suggested that chitotriosidase may also protect individuals against filarial nematode infections and malaria. A mutant allele, which renders chitotriosidase unstable and enzymatical...
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