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Article

Cardiovirus 2A Protein Associates with 40S but Not 80S Ribosome Subunits during Infection

30 Aug 2007

Abstract excerpt

Host translation shutoff induced in picornavirus-infected cells is a well-known phenomenon. The mechanisms by which separate genera of the picornavirus family achieve this shutoff differ. This study examined alterations in the cellular translational components in HeLa cells infected with encephalomyocarditis virus (EMCV), a cardiovirus. In agreement with previous reports, EMCV induced a marked decrease in host...

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PMID: 17728235
DOI: 10.1128/jvi.00185-07

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