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Article

Helicobacter pylori cytotoxin-associated genotype and gastric precancerous lesions.

Journal of the National Cancer Institute - 5 Sept 2007

Plummer Martyn, van Doorn Leen-Jan, Franceschi Silvia, Kleter Bernhard, Canzian Federico, Vivas Jorge, Lopez Gladys, Colin Didier, Muñoz Nubia, Kato Ikuko

Abstract excerpt

BACKGROUND: Helicobacter pylori infection is associated with the development of gastric cancer. Although infection with an H. pylori strain containing the cytotoxin-associated (cag A) gene (a marker for a pathogenicity island) may increase the risk of atrophic gastritis and gastric cancer, the relationship of variants in pathogenic H. pylori genes to the severity and progression of precancerous lesions is not...

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PMID: 17728213
DOI: 10.1093/jnci/djm120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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