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Article

Helicobacter pylori vacuolating cytotoxin genotypes and preneoplastic lesions or gastric cancer risk: a meta-analysis.

Journal of gastroenterology and hepatology - 1 Apr 2016

Abdi Esmat, Latifi-Navid Saeid, Latifi-Navid Hamid, Safarnejad Bahareh

Abstract excerpt

BACKGROUND AND AIM: Disease progression to gastric cancer (GC) occurs in only a small proportion of Helicobacter pylori (H. pylori) infected patients. The bacterium vacuolating cytotoxin A (vacA) gene polymorphisms may determine the clinical consequences. We examined the strength of this association in adult-infected populations and modeled the impact of mean age-standardized incidence rates (ASRs) of GC as a...

Topics

Alleles
Bacterial Proteins
Gastritis, Atrophic
Genetic Variation
Genotype
Helicobacter pylori
Humans
Incidence
Intestines
Metaplasia
Regression Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk

Stomach Neoplasms

Source

Identifiers

PMID: 26648346
DOI: 10.1111/jgh.13256

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