Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of ocular hypopigmentation in Rab38cht/cht mice.

Investigative ophthalmology & visual science - 1 Sept 2007

Brooks Brian P, Larson Denise M, Chan Chi-Chao, Kjellstrom Sten, Smith Richard S, Crawford Mary A, Lamoreux Lynn, Huizing Marjan, Hess Richard, Jiao Xiaodong, Hejtmancik J Fielding, Maminishkis Arvydas, John Simon W M, Bush Ronald, Pavan William J

Abstract excerpt

PURPOSE: To characterize the ocular phenotype resulting from mutation of Rab38, a candidate gene for Hermansky-Pudlak syndrome. METHODS: Chocolate mice (cht, Rab38(cht/cht)) and control heterozygous (Rab38(cht/)(+)) and wild-type mice were examined clinically, histologically, ultrastructurally, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroid Diseases
Share to Electroretinography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hair Color

Share to Hermanski-Pudlak Syndrome

Share to Melanosomes

Share to Pigment Epithelium of Eye

Share to rab GTP-Binding Proteins

Share to Retinal Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 17724166
DOI: 10.1167/iovs.06-1464
PMCID: PMC1989767

Genes

RPE
RAB38
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17724166-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of ocular hypopigmentation in Rab38cht/cht mice.PMID 17724166Read ↗

Mutation of melanosome protein RAB38 in chocolate mice.Semantic proximity Read ↗

Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes.Semantic proximity Read ↗

Loss of REP1 impacts choroidal melanogenesis in choroideremiaSemantic proximity Read ↗

Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotypeSemantic proximity Read ↗

The Cell Biology of Hermansky–Pudlak Syndrome: Recent AdvancesSemantic proximity Read ↗

Variegated expression and delayed retinal pigmentation during development in transgenic mice with a deletion in the locus control region of the tyrosinase gene.Semantic proximity Read ↗

Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosisSemantic proximity Read ↗

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndromeSemantic proximity Read ↗

Conditional Ablation of the Choroideremia Gene Causes Age-Related Changes in Mouse Retinal Pigment EpitheliumSemantic proximity Read ↗

The <i>Dct</i> <sup>-/-</sup> mouse model to unravel retinogenesis misregulation in patients with albinismSemantic proximity Read ↗

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome.Semantic proximity Read ↗

Rab27a regulates the peripheral distribution of melanosomes in melanocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.