Article
A genetic basis for the interrelation of coagulation factors.
Journal of thrombosis and haemostasis : JTH - 1 Sept 2007
Vossen C Y, Callas P W, Hasstedt S J, Long G L, Rosendaal F R, Bovill E G
Abstract excerpt
BACKGROUND: Evidence found in the literature for a strong correlation between coagulation factors suggests that single genes might influence the plasma concentrations of multiple coagulation factors (i.e. pleiotropically acting genes). OBJECTIVE: To determine whether there is a genetic basis for the correlation among coagulation factors by assessing the heritability of interrelated coagulation factors....
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