Article
An Analysis of Five TrkB Gene Polymorphisms in Schizophrenia and the Interaction of Its Haplotype with rs6265 BDNF Gene Polymorphism.
Disease markers - 1 Jan 2020
Suchanek-Raif Renata, Raif Paweł, Kowalczyk Małgorzata, Paul-Samojedny Monika, Zielińska Aleksandra, Kucia Krzysztof, Merk Wojciech, Kowalski Jan
Abstract excerpt
AIM: The BDNF dysfunction in the schizophrenia has been soundly documented. The TrkB gene is a high-affinity receptor of the BDNF that is changed in schizophrenia and mood disorders. The study had two aims: first, to identify whether the five nucleotide polymorphisms (SNPs) in TrkB gene are associated with a diagnosis of schizophrenia; and the latter, if any association exists between the TrkB SNPs and...
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