Article
Association study between the transferrin gene and schizophrenia in the Japanese population.
Neuroreport - 26 Mar 2007
Maeno Nobuhisa, Takahashi Nagahide, Saito Shinichi, Ji Xiaofei, Branko Aleksic, Ishihara Ryoko, Yoshida Keizo, Inada Toshiya, Iidaka Tetsuya, Ozaki Norio
Abstract excerpt
Several lines of evidence, including diffusion tensor imaging and microarray studies, indicate that abnormalities in myelination play an important role in the pathophysiology of schizophrenia. Of myelin and oligodendrocyte-related genes, a significant decrease in the mRNA levels of transferrin in schizophrenics has been reported by both microarray and quantitative polymerase chain reaction studies. We performed...
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