Article
Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies.
Pharmacogenomics - 1 Aug 2007
Zucman-Rossi Jessica, Laurent-Puig Pierre
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the most frequent solid tumors worldwide and represents the third cause of mortality among deaths from cancer. It has been extensively studied in terms of genetic alteration in the last 10 years and our knowledge has dramatically increased in this field, leading to the definition of different altered pathways in hepatocarcinogenesis. Recently, a comprehensive study of...
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