Article
VDR gene variants associate with cognitive function and depressive symptoms in old age.
Neurobiology of aging - 1 Mar 2009
Kuningas Maris, Mooijaart Simon P, Jolles Jelle, Slagboom P Eline, Westendorp Rudi G J, van Heemst Diana
Abstract excerpt
Vitamin D has been recently implicated in brain function. Our objective was to test whether genetic variance in the vitamin D receptor (VDR) gene is associated with cognitive functioning and depressive symptoms in old age. The study was carried out in the prospective population-based Leiden 85-plus Study. All 563 participants of the study were genotyped for Cdx-2, FokI, BsmI, ApaI and TaqI polymorphisms in the...
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