Article
Reduced hippocampal cell differentiation in the subgranular zone of the dentate gyrus in a rat model of type II diabetes.
Neurochemical research - 1 Mar 2008
Hwang In Koo, Yi Sun Shin, Kim Yo Na, Kim Il Yong, Lee In Se, Yoon Yeo Sung, Seong Je Kyung
Abstract excerpt
It has recently been reported that diabetes mellitus is strongly associated with neurodegenerative and functional disorders of the central nervous system. In the present study, we investigated the changes in proliferating neurons in the dentate gyrus of type II diabetic rats using doublecortin (DCX), a marker of progenitors differentiating into neurons. At 4 weeks after birth, there were no differences in the...
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