Article
Glucocorticoid receptor changes associate with age in the paraventricular nucleus of type II diabetic rat model.
Neurochemical research - 1 May 2009
Yi Sun Shin, Hwang In Koo, Chun Myung Sun, Kim Yo Na, Kim Il Yong, Lee In Se, Seong Je Kyung, Yoon Yeo Sung
Abstract excerpt
Diabetes is a metabolic disorder that is associated with the dysregulation of a number of systems within the body. In the present study, we investigated glucocorticoid receptor (GR) immunoreactivity and its protein levels in the paraventricular nuclei of 4-, 12-, 20- and 30-week-old Zucker diabetic fatty (fa/fa, ZDF) and in Zucker lean control (fa/+ or +/+, ZLC) rats, because the progressive induction of diabetes...
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