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Article

Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study.

BMC gastroenterology - 1 Jun 2005

Willis Gavin, Bardsley Vicky, Fellows Ian W, Lonsdale Ray, Wimperis Jennie Z, Jennings Barbara A

Abstract excerpt

BACKGROUND: Although most patients with hereditary haemochromatosis have HFE C282Y mutations, the lifetime risk to HFE C282Y homozygotes of developing fatal diseases such as hepatocellular carcinoma is uncertain. We have carried out a cross-sectional study to determine the proportion of diagnosed hepatocellular carcinoma patients who are homozygous for the HFE C282Y mutation; and to estimate the penetrance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15929796
DOI: 10.1186/1471-230X-5-17
PMCID: PMC1175847

Genes

HFE

Variants

Provenance

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Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study.PMID 15929796Read ↗

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