Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent independent evolution of msp1 polymorphism in Plasmodium vivax and related simian malaria parasites.

Molecular and biochemical parasitology - 1 Nov 2007

Tanabe Kazuyuki, Escalante Ananias, Sakihama Naoko, Honda Masanori, Arisue Nobuko, Horii Toshihiro, Culleton Richard, Hayakawa Toshiyuki, Hashimoto Tetsuo, Longacre Shirley, Pathirana Sisira, Handunnetti Shiroma, Kishino Hirohisa

Abstract excerpt

The Plasmodium MSP-1 is a promising malaria vaccine candidate. However, the highly polymorphic nature of the MSP-1 gene (msp1) presents a potential obstacle for effective vaccine development. To investigate the evolutionary history of msp1 polymorphism in P. vivax, we construct phylogenetic trees of msp1 from P. vivax and related monkey malaria parasite species. All P. vivax msp1 alleles cluster in the P. vivax...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution, Molecular
Share to Merozoite Surface Protein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phylogeny

Share to Plasmodium falciparum

Share to Plasmodium vivax

Share to Selection, Genetic

Share to Sequence Analysis, DNA

Share to Species Specificity

Source

Identifiers

PMID: 17706800
DOI: 10.1016/j.molbiopara.2007.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent independent evolution of msp1 polymorphism in Plasmodium vivax and related simian malaria parasites.PMID 17706800Read ↗

The evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (MSP-9), in Plasmodium vivax and closely related species.Semantic proximity Read ↗

A comparative study of the genetic diversity of the 42kDa fragment of the merozoite surface protein 1 in Plasmodium falciparum and P. vivax.Semantic proximity Read ↗

The origin and diversification of the merozoite surface protein 3 (msp3) multi-gene family in Plasmodium vivax and related parasites.Semantic proximity Read ↗

Orthologous gene sequences of merozoite surface protein 1 (MSP1) from Plasmodium reichenowi and P. gallinaceum confirm an ancient divergence of P. falciparum alleles.Semantic proximity Read ↗

Why Plasmodium vivax and Plasmodium falciparum are so different? A tale of two clades and their species diversitiesSemantic proximity Read ↗

Plasmodium vivax vaccine candidate MSP1 displays conserved B-cell epitope despite high genetic diversity.Semantic proximity Read ↗

Genetic variation and the recent worldwide expansion of Plasmodium falciparum.Semantic proximity Read ↗

Evolutionary history of Plasmodium vivax and Plasmodium simium in the AmericasSemantic proximity Read ↗

Differential sequence diversity at merozoite surface protein-1 locus of Plasmodium knowlesi from humans and macaques in Thailand.Semantic proximity Read ↗

The Origin of Malarial Parasites in OrangutansSemantic proximity Read ↗

Accelerated Diversification of Nonhuman Primate Malarias in Southeast Asia: Adaptive Radiation or Geographic Speciation?Semantic proximity Read ↗

Genetic diversity of Merozoite surface protein 1-42 (MSP1-42) fragment of Plasmodium vivax from Indonesian isolates: Rationale implementation of candidate MSP1 vaccine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.