Article
Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples.
BMC genomics - 17 Aug 2007
Pullat Janne, Fleischer Robert, Becker Nikolaus, Beier Markus, Metspalu Andres, Hoheisel Jörg D
Abstract excerpt
BACKGROUND: Genetic variants in immune regulator genes have been associated with numerous diseases, including allergies and cancer. Increasing evidence suggests a substantially elevated disease risk in individuals who carry a combination of disease-relevant single nucleotide polymorphisms (SNPs). For the genotyping of immune regulator genes, such as cytokines, chemokines and transcription factors, an...
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