Article
Microarray and microfluidic methodology for genotyping cytokine gene polymorphisms.
Human immunology - 1 Oct 2003
Sohni Youvraj R, Cerhan James R, O'Kane Dennis
Abstract excerpt
Cytokine genetic polymorphisms are the subject of disease-association studies that require large-scale human genotyping. Polymerase chain reaction based custom microarrays and microfluidics systems were used to develop genotyping assays for following cytokine polymorphisms: tumor necrosis factor-alpha G-308A, interleukin-4 (IL-4) C-589T, interferon-gamma (CA)n repeats, IL-1RN 86-bp variable number of tandem...
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