Article
Apolipoprotein E genotype and response of carbon monoxide poisoning to hyperbaric oxygen treatment.
American journal of respiratory and critical care medicine - 15 Nov 2007
Hopkins Ramona O, Weaver Lindell K, Valentine Karen J, Mower Chrissa, Churchill Susan, Carlquist John
Abstract excerpt
RATIONALE: Hyperbaric oxygen (HBO2) reduced the incidence of cognitive sequelae 6 weeks after carbon monoxide (CO) poisoning compared with normobaric oxygen (NBO2). The apolipoprotein (APOE) epsilon4 allele predicts unfavorable neurologic outcome after brain injury and stroke. OBJECTIVES: To assess the effects of the epsilon4 allele on 6-week cognitive sequelae after CO poisoning. METHODS: We tested APOE...
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