Article
Apolipoprotein E genotype and outcome in infants with hypoxic-ischemic encephalopathy.
Pediatric research - 1 Mar 2014
Cotten C Michael, Goldstein Ricki F, McDonald Scott A, Goldberg Ronald N, Salhab Walid A, Carlo Waldemar A, Tyson Jon E, Finer Neil N, Walsh Michele C, Ehrenkranz Richard A, Laptook Abbot R, Guillet Ronnie, Schibler Kurt, Van Meurs Krisa P, Poindexter Brenda B, Stoll Barbara J, O'Shea T Michael, Duara Shahnaz, Das Abhik, Higgins Rosemary D, Shankaran Seetha
Abstract excerpt
BACKGROUND: Adults with the apolipoprotein E (APOE) gene alleles e4 and e2 are at high risk of poor neurological outcome after brain injury. The e4 allele has been associated with cerebral palsy (CP), and the e2 allele has been associated with worse neurological outcome with congenital heart disease. This study was done to test the hypothesis that the APOE genotype is associated with outcome among neonates who...
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