Apolipoprotein E4 allele presence and functional outcome after severe traumatic brain injury.

doi:10.1089/neu.2006.0133

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Article

Apolipoprotein E4 allele presence and functional outcome after severe traumatic brain injury.

Journal of neurotrauma - 1 May 2007

Alexander Sheila, Kerr Mary E, Kim Yookyung, Kamboh M Ilyas, Beers Sue R, Conley Yvette P

Abstract excerpt

Presence of the apolipoprotein E (APOE) 4 allele has been associated with increased incidence and faster progression of neurodegenerative diseases, poorer recovery from neurologic insult, and decreased cognitive function in the well-elderly. The specific association between APOE genotype and recovery from severe traumatic brain injury (TBI) is conflicting with many groups finding the APOE 4 allele to be...

Topics

Adult
Apolipoprotein E4
Brain Injuries
Causality
DNA Mutational Analysis
Female
Gene Frequency
Genetic Markers
Genetic Predisposition to Disease
Genetic Testing
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glasgow Coma Scale

Humans

Hypotension

Hypoxia

Male

Middle Aged

Predictive Value of Tests

Source

Open in PubMed

Identifiers

PMID: 17518534
DOI: 10.1089/neu.2006.0133

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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