Article
The XRCC3 Thr241Met polymorphism and breast cancer risk: a case-control study in a Thai population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000
Sangrajrang Suleeporn, Schmezer Peter, Burkholder Iris, Boffetta Paolo, Brennan Paul, Woelfelschneider Andreas, Bartsch Helmut, Wiangnon Surapon, Cheisilpa Arkom, Popanda Odilia
Abstract excerpt
The X-ray repair cross-complementing group 3 gene (XRCC3) belongs to a family of genes responsible for repairing DNA double-strand breaks caused by normal metabolic processes and exposure to ionizing radiation. Polymorphisms in DNA repair genes may alter an individual's capacity to repair damaged DNA and may lead to genetic instability and contribute to malignant transformation. We examined the role of a...
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