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Article

Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease.

Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2007

Schafmayer Clemens, Völzke Henry, Buch Stephan, Egberts Jan, Spille Annika, von Eberstein Huberta, Franke Andre, Seeger Markus, Hinz Sebastian, Elsharawy Abdou, Rosskopf Dieter, Brosch Mario, Krawczak Michael, Foelsch Ulrich R, Schafmayer Anton, Lammert Frank, Schreiber Stefan, Faendrich Fred, Hampe Jochen, Tepel Juergen

Abstract excerpt

BACKGROUND: Genetic susceptibility contributes to the aetiology of gallbladder diseases as shown by multiple epidemiological studies. A major gallstone susceptibility locus (Lith6) was identified in 2003 by quantitative trait locus mapping in mice. Two attractive positional and functional candida...

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Source

Identifiers

PMID: 17696929
DOI: 10.1111/j.1478-3231.2007.01536.x

Genes

APOBEC1
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17696929-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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