Article
Coagulation-related factors, thrombomodulin and protein Z, are not associated with risk for oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Serefoglou Zoe, Yapijakis Christos, Nkenke Emeka, Vassiliou Stavros, Spyridonidou Sofia, Vylliotis Antonis, Nixon Alexander Michael, Neukam Friedrich Wilhelm, Patsouris Efstratios
Abstract excerpt
BACKGROUND: The link between thrombosis and cancer has been well established. Levels of protein Z and thrombomodulin indirectly regulate thrombin productionl and therefore may affect cancer susceptibility. PATIENTS AND METHODS: The functional polymorphisms -13A/G and -33G/A in protein Z and thrombomodulin genes (respectively) influence transcription. The two polymorphisms were investigated in 160 oral cancer...
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