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Article

Altered potassium channel function in the superficial dorsal horn of the spastic mouse.

The Journal of physiology - 1 Oct 2007

Graham B A, Brichta A M, Schofield P R, Callister R J

Abstract excerpt

The spastic mouse has a naturally occurring glycine receptor (GlyR) mutation that disrupts synaptic input in both motor and sensory pathways. Here we use the spastic mouse to examine how this altered inhibitory drive affects neuronal intrinsic membrane properties and signal processing in the superficial dorsal horn (SDH), where GlyRs contribute to pain processing mechanisms. We first used in vitro patch clamp...

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Identifiers

PMID: 17690143
DOI: 10.1113/jphysiol.2007.138198
PMCID: PMC2277054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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