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Article

Role of p14ARF in TWIST-mediated senescence in prostate epithelial cells

10 Aug 2007

Abstract excerpt

Recently, TWIST, a basic helix-loop-helix transcription factor, is suggested to be an oncogene because of its over-expression in many types of human cancer and its positive role in promoting cell survival. The aim of this study was to investigate the role of TWIST on the growth of human epithelial cells. Using two immortalized human prostate epithelial cell lines, we demonstrated that inactivation of TWIST by...

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PMID: 17690110
DOI: 10.1093/carcin/bgm185

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