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Article

Association of EcoRI polymorphism of the metastasis-suppressor gene NME1 with susceptibility to and severity of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2007

Hsieh Yih-Shou, Lee Yao-Ling, Yang Shun-Fa, Yang Jia-Sin, Chen Wei, Chen Shuo-Chueh, Shih Chuen-Ming

Abstract excerpt

BACKGROUND: Human lung cancer cells with high metastatic potential show reduced expression of the metastasis-suppressor gene NME1. However, the biallelic EcoRI polymorphism of this gene has not been studied in lung cancer. With this allelic association study, we aimed to investigate the impact of polymorphisms of the NME1 gene on the susceptibility to and severity of non-small cell lung cancer (NSCLC). METHODS:...

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Share to Carcinoma, Non-Small-Cell Lung
Share to Deoxyribonuclease EcoRI

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Genetic Predisposition to Disease

Share to Lung Neoplasms

Share to NM23 Nucleoside Diphosphate Kinases

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 17688968
DOI: 10.1016/j.lungcan.2007.06.008

Genes

NME1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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