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Article

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.

Molecular and cellular biology - 1 Oct 2007

Tan Nguan Soon, Icre Guillaume, Montagner Alexandra, Bordier-ten-Heggeler Béatrice, Wahli Walter, Michalik Liliane

Abstract excerpt

After an injury, keratinocytes acquire the plasticity necessary for the reepithelialization of the wound. Here, we identify a novel pathway by which a nuclear hormone receptor, until now better known for its metabolic functions, potentiates cell migration. We show that peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) enhances two phosphatidylinositol 3-kinase-dependent pathways, namely, the...

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Identifiers

PMID: 17682064
DOI: 10.1128/MCB.00436-07
PMCID: PMC2168901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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