Article
[The preparation of oligonucleotide chips for detecting BMPR-IB gene polymorphism in sheep].
Yi chuan = Hereditas - 1 Aug 2007
Yang Hua, Zhong Fa-Gang, Wang Xin-Hua, Liu Shou-Ren, Zhu Bin, Xing Jun-Fen, Sun Yue
Abstract excerpt
BMPR-IB gene increases ovulation rate and litter size as a major gene in Chinese Merino, because of 746 A to G mutation. The aim of this study was to make oligonucleotide chips to determine single nucleotide polymorphism (SNP) in BMPR-IB gene. The oligonucleotide chips were manufactured by using six sequence-specific oligonucleotide probes derived from polymorphic regions in the mutation and spotting the probes...
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