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A repertoire of single nucleotide polymorphisms (SNPs) of major fecundity BMPR1B gene among 75 sheep breeds worldwide.

Theriogenology - 15 Apr 2024

Cao Chunna, Zhou Qian, Kang Yuxin, Akhatayeva Zhanerke, Liu Peiyao, Bai Yuheng, Li Ran, Jiang Yu, Zhang Qingfeng, Lan Xianyong, Pan Chuanying

Abstract excerpt

The BMPR1B gene is a major determinant of sheep reproductive capacity. Previous studies revealed that Q249R (FecB) is a profound variant of BMPR1B that influences the ovulation rate and litter size in sheep. However, unlike Q249R locus, the full spectrum of single nucleotide polymorphisms (SNPs) within BMPR1B has not been extensively studied. A systematic screen of SNPs in BMPR1B would facilitate the discovery of...

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PMID: 38401385
DOI: 10.1016/j.theriogenology.2024.02.019

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