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Article

Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models

1 Aug 2007

Abstract excerpt

BACKGROUND: Phage display antibody libraries have been made from the lymphocytes of patients suffering from autoimmune diseases in which the antibodies are known to play a role in the pathogenesis or are important for the diagnosis of the disease. In the case of Celiac Disease, the immune response is directed against the autoantigen tissue transglutaminase. However, despite numerous studies, the role of these...

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PMID: 17678525
DOI: 10.1186/1472-6750-7-46

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