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Article

When EGF is offside, magnesium is wasted.

The Journal of clinical investigation - 1 Aug 2007

Muallem Shmuel, Moe Orson W

Abstract excerpt

Our understanding of magnesium (Mg(2+)) regulation has recently been catapulted forward by the discovery of several disease loci for monogenic disorders of Mg(2+) homeostasis. In this issue of the JCI, Groenestege et al. report that their study of a rare inherited Mg(2+) wasting disorder in consanguineous kindred shows that EGF acts as an autocrine/paracrine magnesiotropic hormone (see the related article...

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Topics

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Share to Protein Precursors
Share to Epidermal Growth Factor
Share to Magnesium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal, Humanized

Share to Cetuximab

Share to Protein Processing, Post-Translational

Share to Renal Tubular Transport, Inborn Errors

Share to TRPM Cation Channels

Source

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Identifiers

PMID: 17671646
DOI: 10.1172/JCI33004
PMCID: PMC1934592

Genes

EGF
DCT
TRPM6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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