Article
Recognition of the CDEI motif GTCACATG by mouse nuclear proteins and interference with the early development of the mouse embryo.
Nucleic acids research - 1 Dec 1991
Blangy A, Léopold P, Vidal F, Rassoulzadegan M, Cuzin F
Abstract excerpt
We have reported previously (1) two unexpected consequences of the microinjection into fertilized mouse eggs of a recombinant plasmid designated p12B1, carrying a 343 bp insert of non-repetitive mouse DNA. Injected at very low concentrations, this plasmid could be established as an extrachromosomal genetic element. When injected in greater concentration, an early arrest of embryonic development resulted. In the...
Topics
- Animals
- Base Sequence
- Chromatography
- Embryonic and Fetal Development
- Mice
- Microinjections
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Oligonucleotides
- Plasmids