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Article

Sequence-based prioritization of nonsynonymous single-nucleotide polymorphisms for the study of disease mutations.

American journal of human genetics - 1 Aug 2007

Jiang Rui, Yang Hua, Zhou Linqi, Kuo C-C Jay, Sun Fengzhu, Chen Ting

Abstract excerpt

The increasing demand for the identification of genetic variation responsible for common diseases has translated into a need for sophisticated methods for effectively prioritizing mutations occurring in disease-associated genetic regions. In this article, we prioritize candidate nonsynonymous single-nucleotide polymorphisms (nsSNPs) through a bioinformatics approach that takes advantages of a set of improved...

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Identifiers

PMID: 17668383
DOI: 10.1086/519747
PMCID: PMC1950793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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