Article
Translation-coupled translocation of yeast fumarase into mitochondria in vivo.
The Journal of biological chemistry - 5 Oct 2007
Yogev Ohad, Karniely Sharon, Pines Ophry
Abstract excerpt
Fumarase represents proteins that cannot be imported into mitochondria after the termination of translation (post-translationally). Utilizing mitochondrial and cytosolic versions of the tobacco etch virus (TEV) protease, we show that mitochondrially targeted fumarase harboring a TEV protease recognition sequence is efficiently cleaved by the mitochondrial but not by the cytosolic TEV protease. Nonetheless,...
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