Article
Sex-related influence of angiotensin-converting enzyme polymorphisms on fibrosis progression due to recurrent hepatitis C after liver transplantation.
Journal of gastroenterology - 1 Jul 2007
Fabris Carlo, Toniutto Pierluigi, Bitetto Davide, Minisini Rosalba, Fornasiere Ezio, Smirne Carlo, Pirisi Mario
Abstract excerpt
BACKGROUND: Experimental evidence and clinical studies suggest that the renin-angiotensin system and its inhibitors may play a role in regulating the mechanisms of liver fibrosis development. The present study aimed to verify whether carriage of specific angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) allelic variants, modulating angiotensin II generation, could affect the outcome of recurrent...
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